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Cocaine Vaccine Research

Up until now, the vaccine has been tested on rats and non-human primates. Biologically, non human primates are said to be closer to humans than rats. The success rate of the cocaine vaccine results has urged the researchers to test the vaccine on humans. The tests conducted on rats injected with the virus and cocaine showed less hyperactive behavior than those mice which were given just cocaine.

Researchers attempted to study the effectiveness of the cocaine vaccine in non-human primates by measuring the amount of cocaine attaching itself to the dopamine transporter. If cocaine reaches the brain it prevents the transporter from carrying dopamine out and attaches itself to the dopamine transporter. This keeps the neurotransmitter active in producing a drug high.

An isotope was attached to the dopamine transporter to measure the amount of tracer attaching to the dopamine receptor in presence or absence of cocaine. The activity of the tracer was seen using a Positron Emission Tomography (PET). There was no change in tracer activity in vaccinated and non- vaccinated primates when cocaine was not given. There was a significant drop in activity of tracer when cocaine was given, in non-vaccinated animals.

This means that in the absence of vaccine, cocaine attaches itself to the dopamine receptor by replacing the tracer. The cocaine occupancy of the dopamine receptor in vaccinated primates was reduced to 20% by use of the vaccine. Previous researches have shown that to produce high cocaine should occupy 47% of the dopamine transporter.

The vaccine was further reported to have lasted 13 weeks in rats and 7 weeks in non-human primates. Researches do not know the amount of vaccine shots that would be required for humans to make it effective. With preliminary results being so satisfying, conducting human trials in near future for the cocaine vaccine gives hope to the cocaine addicts in Johnstown who want to desperately stop using.

Cocaine Vaccine: Methods to Treat Cocaine Addiction in Johnstown

Thousands of people in Johnstown suffer from cocaine addiction, and this has serious consequences as far as healthcare expenses and fatalities are concerned. There are several treatments for cocaine addiction in Johnstown. As far as medications are concerned, methadone works well with heroin addiction, but unfortunately, there is no such alternative for cocaine addiction.

That is why recently scientists have been working on developing a cocaine vaccine. Like methadone, a cocaine vaccine may be able to prevent the pleasurable sensations associated with the addictive.

Heroine Vaccine: The Idea

While treatments options abound, researchers have long been working on the development of a heroin vaccine to reduce dependency on the drug. Millions of people in Johnstown and the rest of the U.S. are addicted to heroin which comes with its own list of associated problems, such as increased incidence of HIV transferred through shared syringes. Not to mention, drug relapse is relatively high in heroin as compared to other drugs.

These and other factors have set the stage for the development of a heroin vaccine. Various reports show that the possibility of heroin vaccine pre-testing is finally here. Till now, tests have been conducted on rats, which have provided positive results. If you know someone who has fallen prey to heroin addiction, these vaccines may provide the possibility of a sober future.

The heroin vaccine creates a barrier between the drug and the brain. By preventing heroin from reaching the brain when it enters the blood stream, the vaccine kills the psychological effect, the high that the drug creates. The vaccine achieves this by triggering the enzymes present in our body to act against heroin. The vaccine would have pieces of the drug which are inactive, and this will train the immune system to create antibodies to counter the effects of heroin in your system.

Consequences of Prescription Drug Abuse

In addition to the physical addiction created by prescription drug abuse, a person may also experience:

Seeking Drug Addiction Treatment in Johnstown? Heres What You Need to Know

Recent stats suggest that almost 10 out of 100,000 people in Johnstown suffer from drug overdose fatalities. This is a 78% increase since 1999. While the collective costs of drug addiction run into billions every year, the number of people who sign up for treatment along with their recovery rates remain low. If you are facing addiction issues yourself, you should know that your actions have social consequences. Ultimately, only the addict can help himself, but signing up for professional treatment substantially boosts the chances of recovery.


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